Cannabinoids To Know: CBC

Written by Cara Wietstock

Cannabichromene (CBC) is one of the more common cannabinoids found in cannabis.

CBC bears a similar structure to other cannabinoids like delta-9 tetrahydrocannabinol (THC). This cannabinoid is known to interact with common CB1 and CB2 receptors in addition to TRPV1 and TRPV2 receptors. The function of the TRPV receptor is regulating and detecting the body’s temperature in relation to pain. The fact that this cannabinoid activates these receptors could be a large part of the medicinal effects of cannabis.


This cannabinoid is not scheduled by the Convention of Psychotropic Substances and is non-psychotropic. CBC has two stereo isomers. A study done on mice showed that the anti-inflammatory activity from CBC is modulated by THC. The British Journal of Pharmacology conducted a study on CBC and CBD in 2011. This study concluded that both CBC and CBD stimulate descending pathways of antinociception. They also cause analgesia by interacting with several target proteins that are involved in nociceptive control.

Another study was done in 2012 that just looked at CBC and its ability to normalize gastrointestinal hypermobility without disrupting transit time for the body’s waste. The study noted that this should be of clinical interest since most gastrointestinal dysmotility drugs cause constipation. The most recent relevant study on CBC took place in 2015 alongside with other phytocannabinoids. These cannabinoids, -specifically CBC, cannabidivarin, and tetrahydrocannabivarin- were studied for their anti-inflammatory effects in relation to chronic acne. The conclusion was that these cannabinoids are in fact a novel anti-acne agent.

With all of this scientific evidence to look at we have to wonder why CBD gets all of the attention. CBC is certainly one of the cannabinoids to keep our eye on. Do you have a favorite cannabinoid? Anything to add here? Tell us in the comments!


Boiling Point: 220°C

Chemical Formula: C21H30O2

Molar Mass: 314.46 g/mol

About the author

Cara Wietstock

Cara began working in the retail cannabis industry of San Francisco, CA in 2011 and continued in that sector for years. In 2015 she dedicated herself to writing full-time. Her passion for the written word and deep respect for the healing properties of the plant have brought her to Terpenes and Testing magazine. She now helps keep us on the cutting edge of scientific cannabis discovery as the Editor-in-Chief of the print publication.

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